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Britain: Calls for Herceptin breast cancer drug and healthcare
rationing
By Paul Mitchell
2 December 2006
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On November 25, the British Medical Journal (BMJ) published
a report entitled Rationing: How much will Herceptin really
cost?
It was widely covered in the UK press. The Guardian
declared, Thousands of patients could be denied life-saving
medicines if hospitals are to pay for the few to be given the
breast cancer drug Herceptin, doctors warn.
The Times proclaimed, Doctors say Herceptin is
a waste of money.
Nearly 9 percent of women will develop breast cancer during
their lifetime, making it one of the most common types of cancer
in women. More than 1 million new cases of breast cancer are diagnosed
worldwide each yearpredominantly in the industrialised world.
About 400,000 people die each year from the disease, although
death rates are declining probably as a result of earlier detection
and improved treatment.
Herceptin is the most well-known of a new generation of drugs,
called monoclonal antibodies, which scientists believe will revolutionise
the treatment of cancer. They are more effective than traditional
treatments because they target individual cancers without damaging
healthy cells, which conventional drugs tend to do. Herceptin
targets a particularly aggressive form of breast cancer, which
is responsible for about 20 percent of cases of the disease. An
experiment with Herceptin in the UK has shown that only 9.4 percent
of women found their cancer returned after using the drug compared
to 17.2 percent who did not use it.
The US Food and Drug Administration approved the use of Herceptin
in 1998 for women with advanced breast cancer, where the disease
has spread to other parts of the body. The department that authorises
drug use in the UK, the National Institute for Health and Clinical
Excellence (NICE), followed suit in 2002. Following a number of
high-profile legal battles by patients with early stage breast
cancer who had been refused Herceptin by their health authorities,
NICE was forced to extend the drugs use to such patients
in July 2006. On November 17, 2006 the FDA also approved the use
of Herceptin for early breast cancer in the US.
Welcoming NICEs decision, Joanne Rule, chief executive
of the charity Cancerbackup, said, From now on treatment
should depend on clinical need and not on where you live, how
much money you have, or how exceptional you are.
The authors of the BMJ report are three doctors in the Department
of Oncology at the Norfolk and Norwich University hospital and
Richard D. Smith, a reader in health economics at the University
of East Anglia.
The doctors complain that NICE has capitulated to high
profile patients, media bias, industry support and political gaming
by approving the use of Herceptin in the treatment of early breast
cancer. In addition, it has failed to provide additional
funding or any suggestion of which services to cut, leaving
medical staff with difficult decisions to make.
The cost for one years treatment with Herceptin in the
UK is around £19,500 ($38,000) and the total bill could
be £100 million per year, or about a quarter of the annual
cancer drug bill for the whole country.
The doctors argue that the £1.7 million cost of treating
75 patients with Herceptin at the Norfolk and Norwich University
hospital will prevent 355 patients with other cancers being treated
with cheaper alternatives. One of the doctors, Ann Barrett, said,
We will be the ones to tell them they are not getting a
treatment that has been proved to be effective, which costs relatively
little, because it is not the treatment of the moment.
Another of the doctors, Tom Roques, said, In an ideal world,
there would be ring-fenced government money to back up NICE decisions.
But we at least need a public debate about how we keep up with
new treatments and expensive treatments in a rationed NHS.
The BMJ report says NICE should be given responsibility to
decide what should be cut to fund newly recommended technologies
or the ability to allocate extra funds for implementation (or
both).
The media has largely ignored any suggestion of extra funds
and fully endorses the claim that rationing is the only alternative
in a market-driven NHS.
Such calls for the rationing of treatment can only result in
a sordid squabbling for resources amongst different sectors of
the health service, rather than addressing the more fundamental
question: Namely, whether humanity can afford a political and
economic system that sacrifices the fruits of science and technology
and their revolutionary implications for medical treatments at
the altar of profit, all in the name of cost effectiveness
and value for money?
In the same week that the doctors from Norfolk and Norwich
University hospital published their report, Prime Minister Tony
Blair announced that British military forces would be given whatever
they want to prosecute the war in Iraq and Afghanistan.
The Centre for Economics and Business Research also revealed that
Christmas bonuses in the City of London are expected to total
a record £8.8 billion, an increase of 18.3 percent on 2005.
Such truly wasteful extravagance received barely a mention
in the same media that was demanding restrictions in health treatment.
It should also be pointed out that the Roche group, manufacturers
of Herceptin, saw total sales increase to £8.5 billion for
the first six month of 2006 and operating profit rise 27 percent
to £1.9 billion. But none of the media, nor the BMJ authors,
suggested that Roche be made to cut its prices, much less questioned
whether it was in societys interest for the drug industry
to be run along profit-making lines.
Should the BMJ authors have really wanted to address the issue
of waste in healthcare, they could have looked much closer to
home.
In May this year the House of Commons public accounts committee
criticised those involved in the construction of the Norfolk and
Norwich University hospital itself, one of the first hospitals
built under the Private Finance Initiative (PFI). This was first
introduced in 1992 by the Conservative government as a means of
privatising essential services by stealth and since expanded under
Labour. Under PFI, private sector corporations design, build,
own and operate public services in return for an annual fee for
the duration of the contract, typically 25 to 35 years.
The Commons committee revealed that a refinancing deal had
lined the pockets of the investors with a windfall
payment of £115 million and an increase in the rate of return
from 16 percent to 60 percent. At the same time management at
the Norfolk and Norwich University hospital announced that they
were heading for a deficit of nearly £15 million and 450
jobs were at risk. Even the Conservative chairman of the committee,
MP Edward Leigh, was forced to complain about the unacceptable
face of capitalism revealed at the hospital.
The only rational solution to the crisis in health care is
a socialist program of providing universal, comprehensive medical
coverage paid for by the government and turning the giant pharmaceutical
firms into public utilities.
See Also:
Britain: Breast cancer patients
legal challenge highlights rationing of health care
[31 March 2006]
Britain: Private capital and
the crisis in the National Health Service
[9 March 2006]
The drug industrys
chokehold on Americas health care
[3 January 2005]
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